The Senior Research Assistant is part of Biomedical Engineering and the Center for Stem Cell Biology at Vanderbilt University.The position will play a key role in diverse research domains spanning development of cell-based therapeutics for diseases such as arthritis and Alzheimer’s disease. It involves working closely with the principal investigator to execute and maintain best laboratory practices for assigned tasks.
The Senior Research Assistant will be responsible for managing selected day-to-day functions of the laboratory including molecular cloning of plasmid DNA, maintenance of IACUC protocols and records, maintenance of mouse colonies, assisting with animal handling procedures such as in vivo imaging, IP/tail vein, or local injections of test compounds, euthanasia, necropsy, dissection, and tissue and cell isolation.
The lab’s mission is to develop and deploy synthetic biology tools to control stem cells for regenerative engineering and in vitro disease modeling. Projects include development of stem cell-based therapeutics for musculoskeletal, autoimmune, and neurodegenerative diseases; creation of high-fidelity models of neurodegenerative diseases via gene editing and rewired signaling modules in pluripotent stem cells; and engineering cells to interface with biomaterials through artificial gene circuits.
Duties and Responsibilities
Additional responsibilities may include ordering supplies/reagents and assisting with media preparation. The position will be prepared to communicate experimental results effectively, maintain rigorous and reliable lab records, and work reliably within a synergistic team cooperatively and with integrity.
Animal husbandry:
– Genotype transgenic mice
– Assist with in vivo imaging protocols
– Assist with compound injection
– Assist with necropsy and dissection
Molecular and cell biological analysis:
– Gel electrophoresis
– Molecular cloning
– RNA/DNA extraction
Assist with daily lab operations:
– Assist in maintaining mammalian cell lines
– Participate in media and buffer formulation
– Assist in maintaining lab instruments
– Assist in maintaining compliance with animal use, biological, and chemical safety protocols
– Assist with inventory and procurement of lab supplies and reagents
– Other tasks as assigned
A bachelor’s degree in a relevant field (e.g., biomedical engineering, biology, biochemistry) is required
The following skills are necessary:
– Experience with semiconductor device physics
– Experience with experiments related to radiation-effects in electronics
– Ability to present research results in journal publications and at professional meetings
– Ability to work as a team member on a wide variety of radiation-effects programs
The following skills are preferred:
– Experience with radiation transport codes (e.g., MRED, Geant4, MCNP, etc.)
– Experience with space radiation environment codes (e.g., CRÈME, Spenvis, etc.)
– Experience with semiconductor-device simulation codes (e.g., Synopsys, Silvaco, etc.)
– Specific experience or skill is strongly preferred.
– Experience with radiation-effects analysis for complex electronic systems
Commitment to Equity, Diversity, and Inclusion
At Vanderbilt University, we are intentional about and assume accountability for fostering advancement and respect for equity, diversity, and inclusion for all students, faculty, and staff. Our commitment to diversity makes us who we are. We have created a community that celebrates differences and lets individuality thrive. As part of this commitment, we actively value diversity in our workplace and learning environments as we seek to take advantage of the rich backgrounds and abilities of everyone. The diverse voices of Vanderbilt represent an invaluable resource for the University in its efforts to fulfill its mission and strive to be an example of excellence in higher education.
Vanderbilt University is an equal opportunity, affirmative action employer. Women, minorities, people with disabilities, and protected veterans are encouraged to apply.
Please note, all candidates selected for an offer of employment are subject to pre-employment background checks, which may include but are not limited to, based on the role for which they have been selected: criminal history, education verification, social media review, motor vehicle records, credit history, and professional license verification.